Endocrine Abstracts

Introduction: The estimated annual incidence of Cushing’s disease ranges from 2 to 4 per million. Bilateral macronodular adrenal hyperplasia (BMAH) accounts for <1% of Cushing’s syndrome causes.Case report: We present a case of 58-year-old man who had been suffering typical clinical signs of hypercortisolism for 5 years. He presented hyperglycemia, arterial hypertension, central obesity, thin skin, hemorrhagic diathesis, edemas, weakness an...

Introduction: Hyperaldosteronism usually presents with hypertension and hypokalemia; however, there is recent evidence of a relationship with the parathyroid hormone. There are different theories to try to explain this relationship. Hyperaldosteronism treatment is medical or surgical depending upon etiology. We present three cases in which treatment solely for hyperaldosteronism also cured hyperparathyroidism.Materials and methods: We report three patien...

Introduction: Langerhans cell histiocytosis (LCH) is a rare disorder with variable clinical presentations. Among the endocrine compromise, the LCH has a predilection for the hypothalamic-pituitary axis. However, primary thyroid involvement is rare and usually related to multisystemic disease.Case Report: We present a 30-year-old woman who requested a medical consultation because of polyuria and was found to have central diabetes insipidus (CDI). The pati...

Introduction: Diabetes Mellitus (DM) and prediabetic states (pre-DM) are well known risk factors for stroke. Admission blood glucose level and its control during hospital stay, help predicting arterial recanalization after thrombolysis and middle and long term prognosis. We analysed recurrence, mortality and nosocomial infectious complications in DM, pre-DM and patients without previous or newly diagnosed DM or pre-DM.Methods: Descriptive analysis in con...

Introduction: The prevalence of brain metastasis from differentiated thyroid carcinoma is 1%. Brain metastasis as the first manifestation of the disease is extremely uncommon.Case report: We present a case of 44-year-old woman with headache and a tumor in right parietal zone. The patient has had multinodular goiter for 15 years, with two dominant nodules in left thyroid lobe. Both of them were isoechoic with hypoechoic halo and measured 2 cm. Fine-needle...

Introduction: Malignancy is an uncommon cause of adrenal incidentaloma in patients without a known diagnosis of cancer. The actual frequency of primary adrenal carcinoma in patients with adrenal incidentaloma is ~2–5%; another 0.7–2.5% have nonadrenal metastases to the adrenal gland. The presence of a nonadrenal primary tumour is exceptional and has been scarcely reported in medical literature.Case report: We present a case of 71-year-old male ...

Introduction: The prolactinoma is the most common functioning pituitary tumour. There are few long-term studies on the optimal duration of treatment with dopamine agonists prolactinoma to ensure healing without recurrence after stopping the medication and do not provide a consensus on it or on withdrawal criteria treatment.Objectives: To establish the prevalence of withdrawal of treatment macroprolactinomas and evaluate criteria prolactinoma cure medical...

Objective: To develop a specific questionnaire to evaluate the satisfaction of diabetic patients with the use of glucometers and evaluate their psychometric properties (feasibility, reliability, and validity).Material and methods: Two stages: i) questionnaire development: a set of 53 items was constructed after a bibliographic review. A panel of six experts and 50 patients concluded a 25-item version of the questionnaire (dimensions: satisfaction, inconv...

Introduction and objectives: Multiple surgeries are associated with many complications in the local recurrence of papillary thyroid carcinoma. Our objective is to evaluate the efficiency of the enolization in the recurrent metastatic cervical lymph nodes in patients with limited nodal disease.Material and methods: We studied 13 patients (six males and seven females) with a mean age of 43±14.4 years with papillary thyroid carcinoma intervened (total ...

Introduction: About 30% of all familial isolated pituitary adenoma (FIPA) and 50% of acromegaly families have a mutation in the aryl hydrocarbon receptor-interacting protein gene (AIP; Chahal, TEM, 2010). The functional role of AIP in somatotroph cells is unknown. Recently, it has been proposed that wild type AIP (wtAIP) is a tumor suppressor gene, role that is lost in the different mutant AIPs (mAIP; Leontiou, JCEM, 2008). In the adenomas, mAIPs are usually foun...